Immunology
The articles listed here are updated regularly and address cutting-edge research addressing the unique immunology found in the liver.
Liver Cancer: A Promising Avenue for More Effective Immunotherapies
Hepatocellular carcinoma is associated with known risk factors such as chronic hepatitis B or C infection, alcohol abuse, and metabolic dysfunction. It is the most common type of liver cancer. Despite major advances in immunotherapy, this cancer is often fatal: around...
Tumor Immune Microenvironment and the Current Immunotherapy of Cholangiocarcinoma
Cholangiocarcinoma (CCA) is a highly heterogeneous malignancy originating from the epithelial system of the bile ducts, and its incidence in recent years is steadily increasing. The immune microenvironment of CCA is characterized by diversity and complexity, with a...
A next-generation treatment for bile duct cancer
Tinengotinib has a unique binding mechanism away from the ATP binding pocket that enables it to target even newly resistant cancer cells. It overcomes acquired resistance by targeting FGFR2 kinase domain mutations. Essentially, by inhibiting a number of different...
The Immunological and Metabolic Landscape in Primary and Metastatic Liver Cancer
The liver is the sixth most common site of primary cancer in humans, and generally arises in a background of cirrhosis and inflammation. Moreover, the liver is frequently colonized by metastases from cancers of other organs (particularly the colon) because of its...
Pediatric Immunotherapy
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